Route 66: The Ultimate American Road Trip

24 Nights

Holiday Highlights

Follow legendary Route 66 on the ultimate American road trip. Discover iconic cities, nostalgic roadside Americana, cowboy country & spectacular landscapes with unforgettable stops including Oklahoma City, Santa Fe, the Grand Canyon and Las Vegas.

 

 

  • Follow the legendary Route 66 from Chicago to Los Angeles
  • Begin among the skyscrapers, architecture and lakefront sights of Chicago
  • Cross the Mississippi and experience the music and character of St Louis
  • Spend time in Oklahoma City, combining Route 66 heritage with cowboy culture, Stockyards City, Bricktown and fascinating First American history
  • Experience classic roadside Americana, neon signs and quirky Route 66 landmarks across Oklahoma, Texas and New Mexico
  • See the iconic Cadillac Ranch outside Amarillo
  • Discover the adobe architecture, Southwestern culture and incredible scenery of Santa Fe and Albuquerque
  • Explore the Painted Desert and Petrified Forest National Park
  • Experience the breathtaking Grand Canyon, one of the great natural wonders of the USA
  • Enjoy the bright lights of Las Vegas before finishing beside the Pacific in Los Angeles and Santa Monica
24 Nights
More USA holiday
From £2,499 pp
Price Breakdown:
Holiday Cost: £2,499 per person
In Destination Cost: £100 per person
Holiday Code: #B6a
Route 66: The Ultimate American Road T...
From £2,499 pp

What's Included

Wide range of dates available
Call 020 3542 8888 for more details

  • Return flights from London
  • 24 nights accommodation
  • Fully insured duration car hire
  • Fully flexible self-drive itinerary
  • Regional departure airports available on request
  • ABTA protected for complete peace of mind

 

Accommodation

3 nights Chicago, Illinois
1 night Springfield, Illinois
2 nights St Louis, Missouri
1 night Springfield, Missouri
1 night Tulsa, Oklahoma
2 nights Oklahoma City, Oklahoma
1 night Amarillo, Texas
1 nights Tucumcari, New Mexico
2 nights Santa Fe, New Mexico
2 nights Albuquerque, New Mexico
1 night Holbrook, Arizona
2 nights Williams / Grand Canyon, Arizona
1 nights Kingman, Arizona
2 nights Las Vegas, Nevada
3 nights Los Angeles, California

Pricing

2026-2027
Bookable All Year Round (seasonal rates may vary)
£2599 pp
Based on 2 adults sharing - London departure 10th April 2027
Prices subject to change and availability

About Route 66: The Ultimate American Road Trip

Chicago to Los Angeles

Follow legendary Route 66 across America on an unforgettable journey from Chicago to Los Angeles. Travel through classic cities, small-town America, desert landscapes and the spectacular Southwest, discovering neon signs, roadside Americana, cowboy culture and some of the Mother Road’s most famous sights along the way.

Chicago, Illinois

Your adventure begins in the birthplace of Route 66. Discover Chicago’s spectacular skyline, lakefront attractions, architecture, blues clubs and deep-dish pizza before setting off along the Mother Road.

Springfield, Illinois

Journey into the heart of Illinois and the city closely associated with Abraham Lincoln. Historic landmarks, classic Americana and Route 66 nostalgia make Springfield a fascinating early stop.

St Louis, Missouri

Meet the mighty Mississippi in St Louis, home to the soaring Gateway Arch. Enjoy great food, music and neighbourhoods before continuing west into Missouri.

Springfield, Missouri

Known as the Birthplace of Route 66, Springfield celebrates its Mother Road heritage alongside classic diners, roadside landmarks and a welcoming slice of small-town America.

Tulsa, Oklahoma

Route 66 takes centre stage in Tulsa, where colourful neon, roadside icons and Art Deco architecture combine with a rich musical heritage and an exciting food scene.

Oklahoma City, Oklahoma

Discover cowboy culture and First American heritage in Oklahoma City. Explore Stockyards City, Bricktown and the city’s Route 66 landmarks for a memorable taste of America’s Heartland.

Amarillo, Texas

Welcome to Texas and the wide-open landscapes of the Panhandle. Amarillo delivers classic Route 66 character, Texas steaks and the wonderfully quirky Cadillac Ranch.

Tucumcari, New Mexico

Few places capture Route 66 nostalgia quite like Tucumcari. Vintage motels, colourful murals and glowing neon signs create a wonderfully preserved slice of the Mother Road.

Santa Fe, New Mexico

Take a break from Route 66 to discover beautiful Santa Fe, where distinctive adobe architecture, Southwestern cuisine, galleries and Native American and Hispanic heritage create one of America’s most characterful cities.

Albuquerque, New Mexico

Rejoin Route 66 in Albuquerque, where the historic highway runs straight through the city. Discover neon signs, Southwestern flavours, Old Town and spectacular high-desert scenery.

Holbrook, Arizona

Step back into classic roadside America in Holbrook, surrounded by Route 66 nostalgia and the remarkable landscapes of Petrified Forest National Park and the Painted Desert.

Williams & Grand Canyon, Arizona

Route 66 charm meets one of the world’s greatest natural wonders. Explore the historic town of Williams before experiencing the breathtaking scale and scenery of the Grand Canyon.

Kingman, Arizona

Surrounded by dramatic desert scenery, Kingman is one of Arizona’s great Route 66 towns and the gateway to a wonderfully nostalgic stretch of the original Mother Road.

Las Vegas, Nevada

Take a spectacular detour to Las Vegas, swapping roadside neon for the dazzling lights of the Strip. Enjoy world-class entertainment, incredible hotels, restaurants and unmistakable Vegas excitement.

Los Angeles, California

Finish beneath the California sunshine in Los Angeles. Discover Hollywood, explore the city’s famous neighbourhoods and head to Santa Monica, where the legendary journey west reaches its iconic Pacific Ocean finale.

Why Book This Holiday?

  • Follow legendary Route 66 from Chicago to Los Angeles
  • Travel through eight incredible US states
  • Experience classic diners, neon signs and roadside Americana
  • Discover Tulsa and Oklahoma City along the Mother Road
  • Explore Santa Fe and Albuquerque in the spectacular Southwest
  • Visit Petrified Forest National Park and the Grand Canyon
  • Experience the bright lights of Las Vegas
  • Finish beside the Pacific Ocean in Los Angeles and Santa Monica
  • The ultimate American self-drive adventure
  • Flights, accommodation and car hire included
  • ABTA protected for complete peace of mind

Get Your Kicks on Route 66

From Chicago’s skyscrapers to Oklahoma’s cowboy country, the deserts of the Southwest and California’s Pacific Coast, Route 66 is more than a road trip. It’s a journey through the heart of America.

Call our expert Travelplanners on 020 3542 8888 to book, enquire or find out more.

24 Nights
More USA holiday
From £2,499 per person
Price Breakdown:
Holiday Cost: £2,499 per person
In Destination Cost: £100 per person
Holiday Code: #B6a

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